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Annona muricata

Common name :Soursop, Graviola
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical Name
Phytochemical ID
Synonym
Part
2D structure
3D structure
Medicinal uses
1
AMYL-CAPROATE
CID_10886
PENTYL HEXANOATE
Plant
N.A
2
Ascorbic acid
CID_54670067
vitamin C
Fruit
Analgesic Antibacterial Antidiabetic Antimigraine
3
Beta carotene
CID_5280489
N.A
Fruit
Antiacne Anticancer Antioxidant Antitumor
4
BETA-SITOSTEROL
CID_222284
Sitosterol Cupreol Azuprostat
Plant
Antibacterial Anticancer Antiestrogenic Antioxidant
5
Caffeic acid
CID_689043
3,4-Dihydroxycinnamic acid
Plant
Antiaging Anticancer Antibacterial Antioxidant
6
Campesterol
CID_173183
Campesterin
Plant
Antioxidant
7
Citric acid
CID_311
2-hydroxypropane-1,2,3-tricarboxylic acid
Plant
Antibacterial Antitumor
8
Citrulline
CID_9750
Plant
Antihepatotic
9
Coclaurine
CID_160487
N.A
Plant
Antioxidant
10
COREXIMINE
CID_7037179
N.A
Plant
Antihypertensive
11
Ethanol
CID_702
ethyl alcohol
Plant
Antibacterial Antiseptic
12
Folacin
CID_135398658
Folate Pteroylglutamic acid
Plant
Antidepressant
13
GABA
CID_119
4-aminobutyric acid 4-Aminobutanoic acid gamma-aminobutyric acid
Plant
Antistress Neuroinhibitory Sedative
14
15
GERANYL-CAPROATE
CID_5365992
Geranyl hexanoate Geranyl caproate
Plant
N.A
16
LIGNOCERIC-ACID
CID_6426598
Dimethyl(pentafluorophenyl)silyl ester
Plant
Antihepatotoxic
17
Malic acid
CID_525
2-Hydroxysuccinic acid 2-Hydroxybutanedioic acid
Plant
Antibacterial Antiseptic Antitubercular Antitumor
18
Methionine
CID_6137
(S)-2-Amino-4-(methylthio)butanoic acid
Fruit
Antidote Antioxidant Glutathionigenic
19
Myristic acid
CID_11005
Tetradecanoic acid
Plant
Antioxidant cancer preventive
20
Niacin
CID_938
Fruit
Antiacrodynic Antidementia Antidiabetic Antispasmodic
21
P-COUMARIC-ACID
CID_637542
4-Hydroxycinnamic acid
Plant
Antioxidant Antitumor
30
TRYPTOPHAN
CID_6305
L-tryptophan
Fruit
Antidementia Antioxidant
29
THIAMIN
CID_1130
vitamin B1
Fruit
Antialcoholic Antidementia
28
STIGMASTEROL
CID_5280794
beta-Stigmasterol
Plant
Antiinflammatory Antioxidant Antiviral sedative
27
STEARIC-ACID
CID_5281
plant
N.A
26
Riboflavin
CID_493570
vitamin B2 Riboflavine Lactoflavin
Fruit
Antimigraine Antioxidant cancer-preventive
25
RETICULINE
CID_439653
N.A
Plant
Antibacterial Antispasmodic
24
PROCYANIDIN
CID_107876
Proanthocyanidins
Plant
AntiHIV Antibacterial Antibiotic Antiedemic Antiviral
23
PARAFFIN
N.A
Plant
Antihemorrhoidal Antiproctalgic
22
PANTOTHENIC-ACID
CID_6613
D-pantothenic acid vitamin B5
Fruit
Antiallergic Cancer preventive

muricata leaf extract, the fraction with enriched flavonoids and acetogenins, pos- sesses antiproliferative activity. The IC50 values were 63 µg/mL, 57 µg/mL, and 87 µg/mL against the prostate cancer cell line, PC-3.

Source : Dr.Duke's phytochemical database 

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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