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AMMPDB VER.1.1
AZADIRACHTA INDICA




1/7
Common name : Neem
Source: freepik.com

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Vernacular Names1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
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Botanical DescriptionAzadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
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Conservation StatusLeast concern source : IUCN
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Medicinal usesHot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No | Phytochemical name | phytochemical ID | synonyms | Part | 2D structure | 3D structure | Medicinal properties |
---|---|---|---|---|---|---|---|
1 | Azadirachtin | CID_5281303 | Azadirachtin A | Seed | Antiecdysic
Antitrypanosomic
| ||
2 | Azadirachtol | CID_23256847 | NA | Fruit | NA | ||
3 | Azadiradione | CID_12308714 | NA | seed | Antifeedant
Antimalarial
| ||
4 | Behenic acid | CID__8215 | Docosanoic acid
1-Docosanoic acid | Fruit | NA | ||
5 | Beta-sistosterol | CID_222284 | Sitosterol
Cupreol
Azuprostat | Leaf ,flower | Androgenic
Anorexic
Antiandrogenic
Antibacterial
Anticancer
Antiestrogenic
Antileukemic
Antilymphomic
Antiophidic
Antipyretic
Antitumor
Antiviral
Cancer preventive | ||
6 | Catechin | CID_9064 | Cianidanol
Catechuic acid | NA | NA | ||
7 | Desacetylnimbin | 10505484 | Deacetylnimbin
6-Deacetylnimbin
6-Desacetylnimbin | Stem, Bark | NA | ||
8 | Desacetylsalannin | NA | NA | NA | NA | ||
9 | Epicatechin | CID_72276 | L-Epicatechin | NA | NA | ||
10 | Gedunin | CID_ 12004512 | Gedunine | Seed | Antimalarial
Cytotoxic | ||
11 | Hyperoside | CID_5281643 | Hyperin
Hyperosid
Quercetin 3-galactoside | Leaf | Antiaging
Antibacterial
Antihepatotoxic
Antioxidant
Antiviral
Cancer preventive
Diuretic | ||
12 | Isomeldenin | CID_76316558 | NA | NA | NA | ||
13 | Isonimbinolide | CID_14136864 | NIMBIN PP | Stem, bark | NA | ||
14 | Kaempferol | CID_5280863 | Kempferol
Robigenin
Kaempherol | Flower | Antiaggregant
Antiallergic
Antibacterial
Anticancer
Antifertility
Anti-inflammatory
Antileukemic
Antioxidant
Antiseptic
Antispasmodic
Antitumor
Cytotoxic
Diuretic | ||
15 | Kaempferol-3-O-beta-D-glucoside | CID_25203515 | kaempferol-3-O-D-glucoside | NA | NA | ||
16 | Kaempferol-3-O-rutinoside | CID_5318767 | Nicotiflorin, Nictoflorin,
NICOTIFLOROSIDE | NA | NA | ||
17 | Khivorin | CID_21596331 | NA | NA | NA | ||
18 | Kulactone | CID_15560423 | NA | NA | NA | ||
19 | Limocinin | CID_14845550 | NA | NA | NA | ||
20 | Margocinin | CID_101529197 | NA | NA | NA | ||
21 | Margolone | CID_189728 | 12-methyl-7-oxopodocarpa-8,11,13-triene-13-carboxylic acid | NA | NA | ||
22 | Myricetin | CID_5281672 | Cannabiscetin
Myricetol
Myricitin | Flower | Antiallergenic
Antibacterial
Antifeedant
Anti gastric
Anti-inflammatory
Antioxidant
Antiseptic
Antiviral
Apoptotic
Cancer preventive
Vasodilator | ||
23 | Nimbandiol | CID_157277 | NA | Stem ,Leaf | Antimalarial
Antiplasmodial | ||
24 | Nimbidiol | CID_11334829 | NA | NA | NA | ||
25 | Nimbin | CID_108058 | NA | Stem ,Bark | Antiallergic
Antihistaminic
Antimalarial
Fungicide
Pesticide
Spermicide | ||
26 | Nimbinin | CID_49863985 | Epoxyazadiradione | Stem ,Bark | Antimalarial
Antiplasmodial
Antiulcer
Cytotoxic
Pesticide
Antiarthritic | ||
27 | Nimbinone | CID_189403 | 12-hydroxy-13-methylpodocarpa-8,11,13-triene-3,7-dione | stem,bark | NA | ||
28 | Nimbiol | CID_11119228 | Nimbial | bark | NA | ||
29 | Nimbolide | CID_12313376 | NA | leaf | Antimalarial
Antiplasmodial
Cytotoxic | ||
30 | Nimocinol | CID_178770 | NIMONOL | Fruit | Anti malarial
Anti plasmodial | ||
31 | Nimosone | CID_189660 | 12,13-dimethoxypodocarpa-8(14),9(11),12-triene-3,7-dione | NA | NA | ||
32 | Ohchinin Acetate | CID_52952322 | NA | NA | NA | ||
33 | Ohchinolide B | CID_6440507 | NA | NA | NA | ||
34 | Quercetin | CID_5280343 | Meletin
Sophoretin
Xanthaurine | Leaf ,Flower | Antiaging
Antiallergic
Anti anaphylactic
Antiarthritic
Antibacterial
Antidepressant
Antimalarial
Antioxidant
Antitumor
Antiviral
Vasodilator | ||
35 | Quercetin-3-O-Beta-D-glucoside | CID_25203368 | Isoquercitrin
quercetin-3-glucoside | NA | NA | ||
36 | Rutin | CID_5280805 | rutoside
Phytomelin
Quercetin 3-rutinoside | Leaf | Antiallergic
Anti apoplectic
Antibacterial
Anticancer
Anticonvulsant
Antidiabetic
Antihemorrhodial
Anihepatotoxic
Antihistaminic
Antioxidant
Antiprotozoal
Antispasmodic
Antisunburn
Antiulcer
Cancer preventive
Immunomodulator
Vasodilator
Vasopressor | ||
37 | Salannin | CID_6437066 | NA | Seed | Antimalarial
Pesticide
Insecticide | ||
38 | Salannol | CID_157144 | NA | NA | NA | ||
39 | Scopoletin | CID_5280460 | Gelseminic acid | Plant | Analgesic
Antibacterial
Antioxidant
Antiseptic
Antitumor | ||
40 | Sugiol | CID_94162 | NA | bark | NA | ||
41 | Vilasinin | CID_185729 | NA | leaf | NA | ||
42 | Zafaral | CID_101355583 | NA | NA | NA |
In DPPH free radical scavenging test, IC50 value of the crude extract was found to be fairly significant (13.81±0.06 µg/ml) while compared with that of the reference standards, ascorbic acid and BHA (2.12±0.02 and 4.87±0.05 µg/ml, respectively).
Source for phytochemicals : Duke's and pubchem
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