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Cannabis sativa.L 

Common  name : bhang, ganja, Wild hemp 
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical Name
Phytochemical ID
Synonym
2D structure
3D structure
Medicinal uses
1
Tetrahydrocannabinol
CID_16078
Dronabinol
Antioxidant Analgesic Anti-inflammatory Ephoriant Antiemetic
2
Cannabidiol
CID_644019
Epidiolex
Analgesic Antioxidant Anti-inflammatory Antipsychotic Anxiolytic Antispasmodic
3
Cannabinol
CID_2543
Cannabinolum 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol
Antibiotic Sedative Oxidant
4
Cannabichromene
CID_30219
Cannabichrome Pentylcannabichromene
Antibiotic Anti-inflammatory Antifungal
5
Cannabigerol
CID_5315659
2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
Antibiotic Antifungal Anti-inflammatory
6
α- pinene
CID_82227
N.A
Anti-inflammatory Stimulant Antibiotics Antineoplastic
7
1,8-cineole
CID_2758
eucalyptol
Anti-inflammatory Antibiotics Antiviral Stimulant
8
Pulegone
CID_442495
N.A
Sedative Antipyretic Memory booster
9
Linalool
CID_6549
3,7-Dimethylocta-1,6-dien-3-ol Linalyl alcohol
Sedative Antidepressant Anxiolytic
10
d- limonene
CID_440917
N.A
Antidepressant Cannabinoid agonist Anti- mutagenic
11
β – caryophyllene
CID_20831623
(+)-caryophyllene
Anti-inflammatory Antimalarial
12
Apigenin
CID_5280443
Chamomile Versulin
Anti-inflammatory Axiolytic Estrogenic
13
β- sitosterol
CID_222284
Sitosterol Cupreol Azuprostat
Anti-inflammatory
14
Quercetin
CID_5280343
Meletin Sophoretin Quercetine
Antioxidant Antiviral Antineoplastic

The methanol extract of high-THC C. sativa strain DQ was found to be cytotoxic to the GBM A172 cell line, with a calculated IC50 of 10.17 µg/mL following treatment for 48 h.

Source : Ashaolu Victoria Oladimeji and MF Valan,2020

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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