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Cedrus deodara (Roxb.ex.D.Don)

Common name : Devdar
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  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical name
Phytochemical ID
Synonym
Part
2D structure
3D structure
1
Deodarin (3’, 4’, 5, 6‑tetrahydroxy‑8‑methyl‑dihydroflavonol)
N.A
Stem bark
2
Himachalol
CID_121536
(+)-2-Himachalen-7-ol
Wood
3
Centradol (2β, 7β‑dihydroxyhimachal‑3‑ene)
N.A
4
Isocentradol (4β, 7β‑dihydroxyhimachal‑2‑one)
N.A
5
Alpha -Himachalene
CID_11830551
N.A
Wood oil
6
beta-Himachalene
CID_11586487
N.A
7
Allohimachalol
CID_10585158
N.A
8
(+)‑longborenol
n.a
9
Atlantone
N.A
Wood
10
himaphenolone
N.A
18
dihydromyricetin
CID_161557
Ampelopsin
17
Cedeodarin (6‑methyltaxifolin)
N.A
Wood
16
dewarenol
N.A
15
Dewarol dewardiol
N.A
14
himadrol
N.A
Heartwood
13
atlantone‑2, 3‑diol
N.A
12
Deodardione
CID_71439784
N.A
11
atlantolone
CID_101949827
N.A
25
Alpha-bisabolol
CID_1549992
Bisabolol
24
Limonene
CID_22311
Dipentene
23
Beta-myrcene
CID_31253
MYRCENE
22
Beta-pinene
CID_14896
Pseudopinene Nopinene
21
Alpha ‑Pinene
CID_440968
N.A
Needle essential oil
20
cedrinoside
N.A
19
cedrin (6‑methyldihydromyrecetin)
N.A
26
β‑caryophyllene
CID_134971569
N.A
33
α‑muurolene
CID_250137072
32
germacrene D
CID_5317570
N.A
31
β‑himachalene
CID_11586487
Himachalene
30
γ‑muurolene
CID_6432308
Naphthalene
29
β‑humulene
CID_5318102
N.A
28
α‑himachalene
CID_319347531
N.A
27
β‑copaene
CID_87529
N.A
34
δ‑cadinene
CID_8145817
N.A
41
quercetin
CID_5280343
Meletin Sophoretin
40
2R, 3R‑dihydromyricetin
CID_161557
Ampelopsin
39
myricetin
CID_5281672
Cannabiscetin
38
Cedrusone A
N.A
37
3’,5’‑Di‑O‑methylmyricetin‑3‑O‑(6”‑O‑acetyl)‑α‑D‑glucopyranoside
N.A
36
Myrecetin‑3‑O‑(6”‑O‑E‑p‑coumaroyl)‑α‑D‑glucopyranoside
N.A
35
γ‑amorphene
CID_12313019
42
2R, 3R‑dihydroquercetin.
CID_439533
Taxifolin
49
1‑dodecanol
CID_8193
Dodecyl alcohol
48
caryophyllene oxide
CID_1742210
beta-Caryophyllene oxide
47
dodecanoic acid
CID_3893
lauric acid
46
linalyl propionate
CID_61098
45
α‑humulene
CID_348291562
44
trans‑caryophyllene
CID_5354499
E-.beta.-caryophyllene
43
α‑myrcene
CID_519324
50
4‑allyloxy‑2‑methyl penta‑en‑2‑ol
CID_156025180
N.A
Petroleum ether extract of needle
57
butyl ester of 5‑oxohexanethioic acid
N.A
56
caryophyllene oxide
CID_1742210
beta-Caryophyllene oxide
55
ethyl ester of dodecanoic acid
CID_7800
54
benzoic acid
CID_243
53
2‑methyl‑5‑phenyl‑5‑pentanonenitrile
CID_12717700
52
butyl acetate
CID_31272
51
2,2‑dimethylpentanal
N.A
58
arabinose
CID_439195
Arabino pyranose
60
xylose
CID_135191
59
mannose
CID_18950
D-Mannopyranose

The IC (50) values varied from 16.4 ng/mL to 116.03 microg/mL depending on the cell line.

Source : sinha.,2019

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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