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Allium sativum.L 

Common name : Garlic, lasun 
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
Phytochemical name
Phytochemical ID
Synonyms
Part
2D structure
3D structure
Medicinal uses
Ajoene
CID_5386591
-
Bulb
Anti-inflammatory Anti septic Antiviral
Alpha-tocopherol
CID_14985
VITAMIN E
Bulb
Antidiabetic Antidementia Anticancer
Beta carotene
CID_5280489
-
Bulb Root Shoot
Anticancer Antitumor Antiulcer
Caffeic acid
CID_689043
3,4-Dihydroxycinnamic acid
Bulb
Antibacterial Anticancer Antioxidant
Citral
CID_638011
GERANIAL
Bulb
Antibacterial Anticancer
Geraniol
CID_637566
Lemonol
Bulb
Anticancer Antiseptic Antitumor
Kaempferol
CID_5280863
Kempferol Robigenin Kaempherol
Plant
Anticancer Antioxidant Antiseptic
linalool
CID_6549
Linalol
Bulb
Antibacterial Antiviral
Niacin
CID_938
nicotinic acid
Bulb
Antidiabetic Antidementia
oleic acid
CID_445639
cis-9-Octadecenoic acid oleate
plant
Antiinflammatory
Pectin
CID_441476
beta-D-galacturonic acid
Bulb
Antibacterial Antidiabetic
Quercetin
CID_5280343
Meletin Sophoretin Quercetine
Bulb
Antibacterial Antioxidant
Rutin
CID_5280805
rutoside
Plant
Anti-inflammatory Antioxidant Antiulcer Antiviral
Salicyclic acid
CID_338
o-hydroxybenzoic acid
Bulb
Antiseptic cancer preventive
Tryptophan
CID_6305
L-tryptophan
Leaf Bulb
Antianxiety Antioxidant
Vanillic acid
CID_8468
Acide vanillique
Bulb
Antioxidant Antiseptic

A. sativum extract had IC50 values of 4.651% for SK-MES-1, which was the most sensitive cell line to garlic extract, 5.482% for DLD-1, 6.131% for MCF-7, and 6.375% for MDA-MB-231, which was the less sensitive cell line to garlic extract.

Source : Pandit et al.,2017

Source for phytochemicals : Duke's and pubchem 

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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