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 Glycosmis pentaphylla

Common name : Ban nimbu 
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical Name
Phytochemical ID
Synonym
2D structure
3D structure
1
Glycoquinone
CID_10544262
N.A
2
Glycocitrine III
N..A
3
Glypentoside A
CID_101396968
N.A
4
Glypentoside B
CID_101396969
N.A
5
Glypentoside C
CID_101396970
N.A
6
Seguinoside F
CID_100953222
N.A
7
Bisglybomine B
N.A
8
Biscarbalexine A
N.A
9
Glybomine B
CID_11208660
N.A
10
Glycoborinine
CID_10446329
3,3,10-Trimethyl-7H-pyrano[3,2-g]carbazol-9-ol
11
Carbalexine A
N.A
12
Glycosmisine A
N.A
13
Glycosmisine B
N.A
14
Glycophymine
CID_135426527
2-Benzylquinazolin-4(1H)-one 2-Benzyl-3H-quinazolin-4-one
15
Glycozolinine
CID_11041703
6-methyl-9H-carbazol-3-ol
16
Noracronycine
CID_5320199
Noracronine 6-hydroxy-3,3,12-trimethylpyrano[2,3-c]acridin-7-one
17
des-N-methylacronycine
CID_6325047
6-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
18
des-N-methylnoracronycine
CID_5479541
6-hydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
19
carbazole
CID_6854
9H-Carbazole Dibenzopyrrole Diphenylenimine
20
3-methylcarbazole
CID_20746
3-Methyl-9H-carbazole
21
glycozolidol
CID_185895
7-Methoxy-6-methyl-9H-carbazol-3-ol
22
glycozolidal
CID_182690
2,6-dimethoxy-9H-carbazole-3-carbaldehyde
23
skimmianine
CID_6760
Skimmianin 4,7,8-Trimethoxyfuro[2,3-b]quinoline Chloroxylonine
24
γ-fagarine
CID_107936
Fagarine 4,8-dimethoxyfuro[2,3-b]quinoline 8-Methoxydictamine
25
R-(+)-platydesmine
N.A
26
melicarpine
N.A
27
robustine
CID_164950
4-methoxyfuro[2,3-b]quinolin-8-ol
28
haplopine
CID_5281846
Heliparvifoline 4,8-dimethoxyfuro[2,3-b]quinolin-7-ol
29
glycopentaphyllon
N.A
30
acutifolin
CID_5316376
N.A
31
glycocitlone C
CID_10709552
N.A
32
arborine
CID_63123
Glycosine 2-Benzyl-1-methylquinazolin-4(1H)-one Arborin
33
dictamine
CID_68085
4-Methoxyfuro[2,3-b]quinoline-
34
γ-skimmianine
N.A
35
1-hydroxy-3,4-dimethoxy-10 methylacridan-9-one
CID_5491358
1-Hydroxy-3,4-dimethoxy-N-methylacridone
36
Biscarbalexine A
N.A

Crude methanolic extract of Glycosmis pentaphylla leaves showed higher antioxidant activity with an IC50 value of 37.62 µg/ml than the result of the present study.

Source : Aye et al.,2019  

Disclaimer: The main motive behind the construction of this database is to compile information from the scientific literature on Indian medicinal plants to aid ongoing research efforts in the field of computational drug discovery.The curated data should be used only for research purposes and not for any self-diagnosis or any medical treatment.

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