top of page

Inula racemosa  

Common name : puskarmul
MapChart_Map (35).png
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical Name
Phytochemical ID
Synonym
2D structure
3D structure
1
Alantolactone
CID_72724
helenine helenin Eupatal
2
isoalantolactone
CID_73285
Isohelenin
3
nunolide (Germacranolide)
N.A
4
Dihydroisoalanto lactone
N.A
5
B-sitosterol
CID_222284
Sitosterol Cupreol Azuprostat
6
D- mannitol
N.A
7
dihydroxinunolide
N.A
8
neo-alantalactone
N.A
9
in-unolise
N.A
10
sesquiterpene lactone (inunol)
N.A
11
alantodiene
N.A
12
1-4-epi-alantolactone
N.A
13
4-alpha,13-dihydroxy-5,7(11)-eudesmadien-12,8-olide
N.A
14
Septuplinolide
N.A
15
macrophyllilactone E
CID_12041559
N.A
16
13-acetyloxy-5,7(11)-eudesmadien-12,8-olide
N.A
17
11 alpha,13-dihydro-2alpha-hydroxy-alantolactone
N.A
18
11,13-dihydroivalin
CID_13944074
N.A
19
Isoalantolactone
CID_73285
20
Daucosterol
CID_5742590
Sitogluside Eleutheroside A

The IC50 (µg/mL) values estimated at 24 h post-treatment in these cells is 5.99 (MDA-MB cells), 9.10 (HeLa cells), and 12.47 (A549 cells).

Source : Manish et al.,2018 
bottom of page