top of page

Ipomoea turpethum 

MapChart_Map (36).png
Common name : nisoth
  • Vernacular Names
    1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
  • Botanical Description
    Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
  • Conservation Status
    Least concern source : IUCN
  • Medicinal uses
    Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World
S.No
Phytochemical name
Phytochemical ID
Synonym
2D structure
3D structure
1
Albumin
N.A
2
Ferric oxide
N.A
3
Lupeol
CID_259846
Fagarasterol Clerodol Monogynol B
4
Alpha- turpethein
N.A
5
Beta-turpethein
N,A
6
Alpha-rhamnose
CID_439710
Alpha-l-rhamnopyranose
7
Beta-rhamnose
CID_439730
beta-L-rhamnopyranose
8
Beta-sitosterol
CID_222284
Sitosterol Cupreol Azuprostat
9
Scopoletin
CID_5280460
Gelseminic acid 7-Hydroxy-6-methoxy-2H-chromen-2-one 6-Methylesculetin
10
Betulin
CID_72326
Betulinol Betuline Trochol
11
Cycloartenol
CID_92110
9beta,19-cyclo-24-lanosten-3beta-ol
12
24-methylene-δ-5-lanosterol
N.A
13
Operculinoside A
CID_54671472
N.A
14
Operculinoside B
CID_54671548
N.A
15
Operculinoside C
CID_54671549
N.A
16
Operculinoside D
CID_54671550
N.A
17
3-(4-hydroxy-phenyl)-N-[2-(4-hydroxy phenyl)-ethyl]-acrylamide
CID_5372945
p-Coumaroyltyramine
18
stigma-5,22dien-3-O-β-D-glucopyranoside
N.A
19
β-sitosterol-β-D-glucoside
N.A
20
22,23-dihydro-α-spinosterol-β-D-glucoside,
N.A
21
salicylic acid (2-hydroxy benzoic acid)
CID_338
2-Hydroxybenzoic acid o-hydroxybenzoic acid 2-Carboxyphenol

The results of the MTT assay revealed that the root extract showed the lowest IC50 values, i.e., 516 μg/mL for MCF-7 and 396 μg/mL for MDA MB-231 cell lines.

Source : Gupta et al.,2017 
bottom of page