Leptadenia reticulata

Common name : Cork Swallow-Wort,dori, jhumka

Taxonomical ID :492004

Vernacular Names

1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
Botanical Description

Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
Conservation Status

Least concern source : IUCN
Medicinal uses

Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World

S.No	Phytochemical Name	Phytochemical ID	Synonym	Part
1	Apigenin	CID_5280443	Chamomile Versulin	Stem bark
2	Diosmetin	CID_5281612	Luteolin 4'-methyl ether	Whole plant
3	Luteolin	CID_5280445	Digitoflavone	Leaves
4	Rutin	CID_5280805	rutoside Phytomelin Quercetin 3-rutinoside
5	Quercetin	CID_5280343	Meletin Sophoretin Quercetine
6	Iso - quercetin	N.A
7	4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-	N.A
8	2H-Pyran, 6-heptyltetrahydro-2,2-dimethoxy-	CID_589211
9	p-coumaric acid	CID_637542	4-Hydroxycinnamic acid
10	α-amyrin	CID_73170	Viminalol
11	β-amyrin	CID_73145	Amyrin beta-Amyrenol
12	Lupeol	CID_259846	Fagarasterol Clerodol Monogynol B
13	Simiarenol	CID_12442794	beta-Simiarenol
14	Phytol	CID_5280435	trans-Phytol
15	Benzene carboxylic acid	N.A
16	Ethyl hydrogen succinate	N.A
17	Hexadecanoic acid, ethyl ester	CID_12366	Ethyl hexadecanoate
19	9,12-Octadecadienoic acid, ethyl Ester	CID_5365672	N.A
18	4-Oxazolecarboxylic acid, 4,5-dihydro-2-phenyl-, 1-methylethyl ester	CID_589632	N.A
20	9-Octadecenoic acid, ethylester	N.A
21	Dodecanoic acid	CID_3893	lauric acid
22	n-Hexadecanoic acid	CID_985	palmitic acid
23	3-Hydroxy-4-methoxybenzoic acid	CID_12575	Isovanillic acid
24	6-Octadecenoic acid, (Z)	N.A
25	Pentadecanoic acid	CID_13849	Pentadecylic acid
26	Tetradecanoic acid	CID_11005	MYRISTIC ACID
27	Deniculatin	N.A		Aerial parts
28	Leptaculatin	N.A		Aerial parts
29	Reticulin	CID_10233		Aerial parts
30	β-sitosterol	CID_222284
31	Stigmasterol	CID_5280794	Stigmasterin
32	Benzaldehyde, 3-hydroxy-4-methoxy-	CID_12127	ISOVANILLIN
33	2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-	CID_27209	Dihydroactinidiolide
34	Glycerin	CID_753
35	Hentricontanol	CID_68345		Leaves/twigs
36	Methyl 6-deoxy-2-O-methyl-	N.A
37	2-Methoxy-4-vinylphenol	CID_332	4-vinylguaiacol 4-Hydroxy-3-methoxystyrene p-Vinylguaiacol
38	Meso-inositol	CID_892	inositol myo-inositol Scyllo-inositol Muco-Inositol epi-Inositol
39	Z-2-Octadecen-1-ol
40	1-Penten-4-one, 2-acetyl-1-dimethylamino- ((Z)- or (E)-)	CID_5371497	N.A
41	Phenol, 2,6-dimethoxy-	CID_7041	Syringol
42	Phenol, 2,6-dimethoxy-4-(2-propenyl)-	CID_226486	Methoxyeugenol
43	Phenol, 2,4-bis(1,1-dimethylethyl)-	CID_7311	N.A
44	2-Propanone, 1-(ethylthio)	N.A		Roots/stem/leaves
45	α-tocopherol	CID_57393415	N.A
46	2,6,8-Trimethylbicyclo[4.2.0]oct-2-ene-1,8-diol	CID_580092
47	n-triacontane	CID_12535

The methanolic extract exhibited moderate antioxidant activity with IC50 value of 510.15 µg/mL.

Source : Mohanty et al.,2019

3D phytochemicals

AMMPDB VER.1.1

Leptadenia reticulata

Common name : Cork Swallow-Wort,dori, jhumka

Source : Mohanty et al.,2019