Mallotus phillipensis

Mallotus philippensis

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Common name : kamal,Kabila

Taxonomical ID:316645

Vernacular Names

1. Assamese : Mahaneem. Maha-neem 2. Bengali : Neem 3. English : Indian Lilac, Margosa, Margosa tree, Neem,Neem tree 4. Gujarati : Limba 5. Hindi : Neem 6. Irula : Veeppa, maram 7. Kannada : Bevu/ Kirubevu, Turakabevu 8. Malayalam : Ariyaveppu, Ayurveppu, Kaippanveppu , Nimbam, Vembu, Veppu 9. Marathi : Nimbay 10. Tamil : Sengumaru, Vembu, Veppa, Veppai 11. Telugu : Vepa Source : FRLHT’s ENVIS
Botanical Description

Azadirachta indica is a tropical evergreen of the MELIACEAE family that grows up to 25 m high. It has rough dark brown bark with wide longitudinal fissures separated by flat ridges. The leaves are compound, imparipinnate, each comprising 5-15 leaflets that are arranged in alternate pairs with terminal leaflets. The compound leaves are themselves alternating with one another. The thin, lanceolate leaflets measure about 6 cm long and 2 cm broad. It bears many flowered panicles, mostly in the leaf-axils. The sepals are ovate and about 1 cm long with sweet scented white oblanceolate petals. It produces yellow drupes that are ellipsoid and glabrous, 12-20 cm long. Source : Medicinal plants of the world: chemical constituents, traditional and modem medicinal uses by Ivan Ross (Volume 2 )
Conservation Status

Least concern source : IUCN
Medicinal uses

Hot water extract of the bark is taken orally by the adult female as a tonic and emmenagogue. The hot water extract of the dried fixed oil is taken orally as an emmenagogue. Anthraquinone fraction of the dried flower, fruit and leaf is taken orally for leprosy. Hot water extract of the flower and leaf is taken orally as an antihistorical remedy, and is used externally to treat wounds. The dried flowers are taken orally for diabetes. Hot water extract of the dried fruit is used for piles and externally for skin diseases and ulcers. Hot water extract of the entire plant is taken orally as an anthelmintic, an insecticide and a purgative. Juices of the bark of Andrographis paniculate, Azadirachta indica and Tinospora cordifolia are taken orally as a treatment for filariasis. Hot water extract of the bark is taken with water, orally before breakfast, for leprosy. The extract is also taken for fever and diabetes, and as a tonic, refrigerant, anthelmintic and antiperiodic. The fresh fruit is used externally for leprosy. Fruit, leaf and root, ground and mixed with dried ginger and "trifala", a preparation consisting of the powdered fruit of Terminalia bellerica (Gaertn.) Roxb., T. Chebula Retz, and Emblica officinalis Gaertn., is taken orally with lukewarm water to treat common fevers. Leaf juice is administered by intravenous infusion for chronic skin diseases, and is taken orally as an anthelmintic. Source : Medicinal Plants of the World

S.No	Phytochemical Name	Phytochemical ID	Synonym	Part
1	Coroglaucigenin	CID_12302399	N.A	Seeds
2	Corotoxigenin	CID_12302397	3,14-Dihydroxy-19-oxocard-20(22)-enolide, (3.beta.,5.alpha.)-	Seeds
3	Coroglaucigenin L-rhamnoside	N.A		Seeds
4	Corotoxigenin L-rhamnoside			Seeds
5	Betulin	CID_72326	Betulinol Trochol Betuline	Stem bark
6	Betulin-3-acetate	CID_479957	3-Acetylbetulin	Heartwood
7	Lupeol	CID_259846	Fagarasterol Clerodol Monogynol B	Heart wood
8	Lupeol acetate	CID_92157	Lupeyl acetate 3-Acetyllupeol	Heart wood
9	Friedelin	CID_91472	Friedeline	Stem bark
10	2β-hydroxy-D: A-friedooleanan-3-one	N.A		Stem bark
11	3-hydroxy-D: A-friedoolean- 3-en-2-one	N.A		Stem bark
12	3α-hydroxy-D: A-friedooleanan-2-one	N.A		Stem bark
13	Acetylaleuritolic acid	CID_161616	Maprounic Acid Acetate 3-acetylaleuritolic acid	Bark
14	Kamaladiol	N.A		Stem bark
15	2β-acetoxy-22β-hydroxy olean-18-ene or Kamaladiol-3-acetate	N.A		Stem bark
16	α-amyrine	CID_73170	Viminalol	Bark
17	Kamalachalcone A	N.A		Fruit
18	Kamalachalcone B	N.A		Fruit
25	Isorottlerin	CID_5318656	N.A	Fruit
24	Isoallorottlerin	N.A		Fruit
23	4'-hydroxy-isorottlerin	CID_5318333	N.A	Fruit
22	Rottlerin	CID_5281847	Kamalin	Fruit
21	Kamalachalcone E	N.A		Fruit
20	Kamalachalcone D	CID_101721040	N.A	Fruit
19	Kamalachalcone C	CID_101721039	N.A	Fruit
34	8-cinnamoyl-5,7-dihydroxy-2,2,6-trimethylchromene	CID_85441307	N.A	Flower
33	8-cinnamoyl-2,2-dimethyl-7-hydroxy-5-methoxychromene	N.A		Flower
32	Mallotophilippen F	N.A		Flower
31	Mallotophilippen E	CID_10458296	N.A	Fruit
30	Mallotophilippen D	CID_9983046	N.A	Fruit
29	Mallotophilippen C	CID_10050581	N.A	Fruit
28	Mallotophilippen B	CID_10205431		Fruit
27	Mallotophilippen A	CID_10185281	N.A	Fruit
26	Methylene-bis-methyl phloro acetophenone	N.A		Fruit
35	5, 7-dihydroxy-8-methyl-6-prenylflavanone	CID_42607875	N.A	Fruit powder kamala
36	6, 6-dimethylpyrano (2'', 3'': 7, 6)-5-hydroxy-8-methylflavanone	N.A		Fruit powder kamala
37	3'-prenylrubranine	CID_42607682		Fruit
38	Bergenin	CID_66065	N.A	Heartwood, bark and leaves
39	11-O-Galloylbergenin	CID_56680102		Stem wood
40	6-O-Galloylbergenin	N.A		Leaves
41	Norbergenin	CID_73192	N.A	Leaves
42	3-O-galloylnorbergenin	N.A		Leaves
43	Tergallic acid dilactone	N.A		Leaves
44	Corilagin	CID_73568		Leaves
45	Geraniin	CID_3001497		Leaves
46	Furosin	CID_10416810	N.A	Leaves
47	Mallotinic acid	CID_10056140	N.A	Leaves
48	Mallotusinic acid	CID_16131237		Leaves
49	Flavogallonic acid	CID_71308199	N.A	Leaves
50	Brevifolin carboxylic acid	CID_9838995		Leaves
51	2,3-(S)-hexahydroxy diphenoyl-D-glucose	N.A		Leaves
52	Repandusinic acid A monopotassium salt	N.A		Leaves
53	α-Kamlolenic acid	CID_5282949		Seed
54	β-Kamlolenic acid	CID_5282950	N.A	Seed
55	Linolenic acid	CID_5280934	alpha-Linolenic acid	Seed
56	Oleic acid	CID_ 445639	N.A	Seed
57	Eicosenoic acid	N.A		Seed
58	Palmitic acid	CID_985		Seed
59	Stearic acid	CID_5281		Seed
60	β-Sitosterol	CID_222284	Sitosterol Cupreol Azuprostat	Seed
61	Daucosterol	CID_5742590		Seed

Compounds rottlerin and shikimic acid exhibited promising inhibitory activity with IC50 values of 0.89 ± 0.33 µg/mL (MIC 2.06 ± 0.41 µg/ mL) and 7.59 ± 0.42 µg/mL (MIC 11.56 ± 0.35 µg/mL), respectively.

Source : Kumar et al.,2021

3D phytochemicals

AMMPDB VER.1.1

Mallotus philippensis

Common name : kamal,Kabila

Source : Kumar et al.,2021